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3-dimethylamino-1-phenyl-propan-1-ol

  • Product Name 3-dimethylamino-1-phenyl-propan-1-ol
  • cas 5554-64-3
  • purity 99%
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1.What is the 3-dimethylamino-1-phenyl-propan-1-ol ?

3-Dimethylamino-1-phenyl-1-propanol is a useful synthetic intermediate. It can be used to prepare phenoxyphenyl diamine-based histamine H3 antagonists with serotonin reuptake inhibitor activities. It is also used to synthesize indolyl aryl propanamines as dual acting norepinephrine and serotonin reuptake inhibitors.

3-dimethylaminopropiophenone
3506-36-3

3-dimethylaminopropiophenone

N,N-dimethyl-3-hydroxy-3-phenylpropylamine
5554-64-3

N,N-dimethyl-3-hydroxy-3-phenylpropylamine

Conditions
Conditions Yield
With sodium tetrahydroborate; In water; at 0 - 20 ℃;
91%
With lithium aluminium tetrahydride;
With aluminium trichloride; aluminum isopropoxide; isopropyl alcohol;
With sodium tetrahydroborate;
With sodium tetrahydroborate; In ethanol;
With sodium borohydrid; In ethanol;
With sodium tetrahydroborate; In methanol;
With sodium tetrahydroborate; In ethanol; at 0 - 20 ℃;
3-(dimethylamino)propiophenone hydrochloride
879-72-1

3-(dimethylamino)propiophenone hydrochloride

N,N-dimethyl-3-hydroxy-3-phenylpropylamine
5554-64-3

N,N-dimethyl-3-hydroxy-3-phenylpropylamine

Conditions
Conditions Yield
With methanol; sodium tetrahydroborate; sodium hydroxide; at 20 ℃; for 1h; pH=12 - 13; Cooling with ice;
96%
3-(dimethylamino)propiophenone hydrochloride; With potassium hydroxide; In water;
With methanol; sodium tetrahydroborate; potassium hydroxide; at 0 - 22 ℃; for 1.5h;
95%
With diisobutylaluminium hydride; In tetrahydrofuran; dichloromethane; for 2h; Ambient temperature;
92%
With sodium tetrahydroborate; sodium hydroxide; In methanol; water; at 10 - 15 ℃; for 3.5h;
92%
With sodium hydroxide; sodium tetrahydroborate; In ethanol; for 2.5h; Heating;
85%
With sodium hydroxide; sodium tetrahydroborate; In ethanol; 1) 20 deg C, 12 h, 2) reflux, 2h;
82%
With potassium hydroxide; sodium tetrahydroborate; In methanol; water; at 20 ℃; for 24h;
With sodium tetrahydroborate; In water; at 0 - 23 ℃; for 2h;
With sodium borohydrid; potassium carbonate; In methanol; water;
With sodium tetrahydroborate; sodium hydroxide; In water; at 0 - 45 ℃;
With sodium tetrahydroborate; sodium hydroxide;
With [(κ2-2-(diphenylphosphanyl)-N-(furan-2-ylmethyl)ethaneamine)Ru(H)(Cl)(CO)(PPh3)]*2toluene; hydrogen; potassium hydroxide; In water; isopropyl alcohol; at 60 ℃; for 36h; under 7500.75 Torr; Catalytic behavior; Inert atmosphere; Autoclave; Glovebox;

2.What is the CAS number for 3-dimethylamino-1-phenyl-propan-1-ol ?

The CAS number of 3-dimethylamino-1-phenyl-propan-1-ol is 5554-64-3.

More information of 3-dimethylamino-1-phenyl-propan-1-ol 5554-64-3 are:

CAS?Number

5554-64-3

Density

1.011 g/cm3

Melting Point

47-48℃

Boiling Point

284.4 °C at 760 mmHg

Flash Point

99.8 °C

HS CODE

2922199090

PSA

23.47000

LogP

1.67170

Pka

14.21±0.20(Predicted)

3.What are another words for 3-dimethylamino-1-phenyl-propan-1-ol ?

Synonyms?for?3-dimethylamino-1-phenyl-propan-1-ol 5554-64-3:Benzylalcohol,α-[2-(dimethylamino)ethyl]-(6CI,7CI,8CI);3-Dimethylamino-1-phenyl-1-propanol;N,N-Dimethyl-3-hydroxy-3-phenylpropylamine;N,N-Dimethyl-3-phenyl-3-hydroxypropylamine;

4.What is the molecular formula of 3-dimethylamino-1-phenyl-propan-1-ol?

The chemical formula of ?3-dimethylamino-1-phenyl-propan-1-ol is?C11H17NO which containing 11 Carbon atoms,17 Hydrogen atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??3-dimethylamino-1-phenyl-propan-1-ol?is 179.262.

5.What is 3-dimethylamino-1-phenyl-propan-1-ol (5554-64-3) used for?

3-Dimethylamino-1-phenyl-propan-1-ol is an organic compound characterized by its amine and phenol functional groups. It is a versatile synthetic intermediate with potential applications in the pharmaceutical industry due to its ability to form various biologically active compounds.

Relevant articles related to 3-dimethylamino-1-phenyl-propan-1-ol:

Article

Source

Fluoxetine scaffold to design tandem molecular antioxidants and green catalysts

Bortoli, Marco,Gianoncelli, Alessandra,Ongaro, Alberto,Orian, Laura,Oselladore, Erika,Ribaudo, Giovanni,Zagotto, Giuseppe

, p. 18583 - 18593 (2020/06/08)

3-[(BENZO[D][1,3]DIOXOLAN-4-YL)-OXY]-3-ARYLPROPYLAMINE TYPE COMPOUNDS AND APPLICATIONS THEREOF

-

Paragraph 0066, (2018/02/02)

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